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Reverse Yeast Two-hybrid System to Identify Mammalian Nuclear Receptor Residues that Interact with Ligands and/or Antagonists
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Reverse Yeast Two-hybrid System to Identify Mammalian Nuclear Receptor Residues that Interact with Ligands and/or Antagonists

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Non-steroidal ligands for steroid hormone receptors

X Lin1, V Huebner

  • 1Chiron Corporation, Small Molecule Drug Discovery, Emeryville, CA 94608, USA. xiaodong_lin@cc.chiron.com

Current Opinion in Drug Discovery & Development
|August 4, 2009
PubMed
Summary

This review highlights novel non-steroidal ligands for key steroid receptors like estrogen, progesterone, and androgen receptors. These compounds offer therapeutic potential in cancer and hormone therapies.

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