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Generation of Genetically Modified Mice through the Microinjection of Oocytes
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Transgenic and targeted mutant mice in drug discovery

U Rudolph1, H Mohler

  • 1ETH and University of Zürich, Winterthurerstrasse 190, CH-8057 Zürich, Switzerland. rudolph@pharma.unizh.ch

Current Opinion in Drug Discovery & Development
|August 4, 2009
PubMed
Summary

Genetically-modified animals are crucial for drug discovery, aiding target identification and disease modeling. Advanced techniques enable precise gene regulation and functional analysis, accelerating therapeutic development.

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