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Related Concept Videos

Depression: Overview01:18

Depression: Overview

Depression is a prevalent mental illness marked by persistent sadness and lack of interest in previously enjoyable activities. It can take several forms, including major depression, persistent depressive disorder, and bipolar I and II disorders. Symptoms range from emotional changes like chronic worry to physical changes like sleep disturbances and suicidal thoughts. From a neurobiological perspective, depression is believed to be triggered by abnormalities in the brain's prefrontal cortex,...
Long-term Depression01:05

Long-term Depression

Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
Depressive Disorders: MDD and Dysthymia01:27

Depressive Disorders: MDD and Dysthymia

Depressive disorders are a group of mental health conditions characterized by pervasive feelings of sadness, diminished pleasure in life, and a significant impact on daily functioning. These conditions are most prevalent in individuals during their 30s and affect women at twice the rate of men. Contrary to popular belief, younger individuals are generally more susceptible to these disorders than older adults. Two key types of depressive disorders include Major Depressive Disorder (MDD) and...

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Related Experiment Video

Updated: Jun 21, 2026

Robotically Delivered fMRI-Guided Personalized Transcranial Magnetic Stimulation Therapy for Treatment-Resistant Depression
13:18

Robotically Delivered fMRI-Guided Personalized Transcranial Magnetic Stimulation Therapy for Treatment-Resistant Depression

Published on: April 10, 2026

Effectiveness of a depression disease management program in improving depression and work function--a pilot study.

Kara Zivin1, Kevin Kerber, Julie Kuebler

  • 1Dept. of Veterans Affairs, Ann Arbor, Michigan, USA. kzivin@umich.edu

International Journal of Psychiatry in Medicine
|August 5, 2009
PubMed
Summary

Depression care management improved patient depression and work function outcomes over time. These improvements were consistent across primary care and specialty mental health settings, demonstrating the program's broad effectiveness.

Related Experiment Videos

Last Updated: Jun 21, 2026

Robotically Delivered fMRI-Guided Personalized Transcranial Magnetic Stimulation Therapy for Treatment-Resistant Depression
13:18

Robotically Delivered fMRI-Guided Personalized Transcranial Magnetic Stimulation Therapy for Treatment-Resistant Depression

Published on: April 10, 2026

Area of Science:

  • Mental Health
  • Primary Care
  • Collaborative Care

Background:

  • Depression significantly impacts work function.
  • Effective depression management strategies are crucial for improving patient outcomes.
  • The Michigan Depression Outreach and Collaborative Care (M-DOCC) program aims to enhance depression care.

Purpose of the Study:

  • To compare depression and work function outcomes in primary care versus specialty mental health settings within the M-DOCC program.
  • To investigate the relationship between depressive symptoms and workplace functioning over time for M-DOCC enrollees.

Main Methods:

  • Mixed model and logistic regression analyses were employed.
  • Patient data from primary care and specialty mental health settings were analyzed.
  • Longitudinal assessment of depression and work function was conducted.

Main Results:

  • Treatment setting (primary care vs. specialty mental health) did not predict depression or work function outcomes.
  • Patients in both settings showed concurrent, significant improvements in depression and functional impairment.
  • Greater case severity and more severe side effects were associated with less improvement over time.

Conclusions:

  • The M-DOCC program effectively improved depression and work function outcomes over time.
  • Improvements were observed regardless of whether patients received care in primary or specialty settings.
  • Depression care management is a viable approach for diverse patient populations.