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[Rotavirus diarrhea in children hospitalized in Wrocław clinics]
G Gościniak1, B Sobieszczańska, K Grzybek-Hryncewicz
1Katedra i Zakład Mikrobiologii Akademii Medycznej we Wrocławiu.
Insights
Rotaviruses cause 25% of diarrhea in young children, particularly infants. The Rotazyme II test offers superior sensitivity for detecting these common pediatric infections.
Area of Science:
- Pediatric Infectious Diseases
- Virology
- Gastroenterology
Background:
- Diarrhea is a significant health concern in children aged 0-3 years.
- Rotavirus is a common etiological agent of gastroenteritis in this age group.
- Co-infections with other enteric pathogens can complicate diagnosis and treatment.
Purpose of the Study:
- To determine the prevalence of rotavirus infections in young children with diarrhea.
- To identify the age groups and seasonal patterns associated with rotavirus infections.
- To compare the diagnostic sensitivity of different rotavirus detection tests.
Main Methods:
- A study involving 250 children aged 0-3 years with diarrhea.
- Detection of rotaviruses using diagnostic tests.
- Identification of co-infections with specific bacterial pathogens.
- Comparative analysis of Rotazyme II, Rotalex, and Rota-kit test sensitivities.
Main Results:
- Rotaviruses were detected in 25% of the children studied.
- Highest rotavirus prevalence was observed in infants aged 0-3 months (29.6%) and 6-12 months (21.8%).
- Rotavirus infections peaked in frequency during February.
- Co-infections with enteropathogenic Escherichia coli, Salmonella, and Campylobacter jejuni occurred in 26% of cases.
- The Rotazyme II test demonstrated higher sensitivity compared to Rotalex and Rota-kit.
Conclusions:
- Rotavirus is a prevalent cause of diarrhea in young children, with distinct age and seasonal patterns.
- Co-infections with bacterial pathogens are common in children with rotavirus.
- Rotazyme II is a more sensitive diagnostic tool for rotavirus detection in pediatric diarrhea cases.
Abstract:
Studies have been performed in 250 children aged 0 to 3 years suffering from diarrhoea. Rotaviruses have been founded in 25% of cases, most frequently in children aged 0 to 3 months (29.6%), and 6 to 12 months (21.8%). Frequency of rotavirus infections was highest during February. In 26% of subjects studied the coexisting infection with enteropathogenic Escherichia coli strains or Salmonella and Campylobacter jejuni has been observed. The Rotazyme II test is more sensitive than the Rotalex and Rota-kit tests.