Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Gastritis II: Pathophysiology01:26

Gastritis II: Pathophysiology

The pathophysiology of gastritis begins with the colonization of the stomach lining by Helicobacter pylori (H. pylori). This bacterium spreads mainly via the oral-oral route through saliva or shared utensils, and can also be transmitted in overcrowded or unhygienic environments through contaminated water, despite its brief survival outside the body.ColonizationOnce ingested, H. pylori enters the stomach and begins colonization by navigating through the mucus layer lining the stomach wall. It...
Gastritis-I: Introduction and Types01:27

Gastritis-I: Introduction and Types

Gastritis, defined by the inflammation or irritation of the stomach lining or gastric mucosa, manifests in several distinct forms: acute, chronic, reactive, and a specific subtype known as autoimmune metaplastic atrophic gastritis.
Acute gastritis presents as a sudden inflammation triggered by various stressors to the stomach lining, such as exposure to corrosive agents, local irritants like aspirin and other NSAIDs, alcohol consumption, radiation therapy, physical trauma, severe burns, sepsis,...
Pyloric Obstruction01:11

Pyloric Obstruction

Pyloric obstruction, also referred to as gastric outlet obstruction, is a condition characterized by narrowing or blockage at the pylorus—the muscular valve regulating the flow of stomach contents into the duodenum. When this passage becomes impaired, the stomach cannot effectively empty its contents into the small intestine. This disruption leads to a range of gastrointestinal symptoms, including early satiety, bloating, epigastric pain, postprandial nausea, persistent vomiting, and...
What is Monogastric Digestion?01:50

What is Monogastric Digestion?

The human body contains a monogastric digestive system. In a monogastric digestive system, the stomach only contains one chamber in which it digests food. Several other animal species also have monogastric digestive systems, including pigs, horses, dogs, and birds. This chapter, however, focuses on the human digestive system.
Gastritis III: Clinical Manifestations and Management01:23

Gastritis III: Clinical Manifestations and Management

The clinical manifestations of gastritis can vary depending on the cause and type of gastritis, but some common symptoms may include the following.
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...
Hormones Secreted by the Stomach01:25

Hormones Secreted by the Stomach

Enteroendocrine cells, accounting for only 1% of stomach epithelial cells, play a significant role in digestion and are classified by their digestive hormone secretions.
Each of these hormones secreted by different enteroendocrine cells plays a unique role in digestion. Here are a few examples:

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Five Advances in the Last 50 Years That Have Impacted Endocrine Surgery.

World journal of surgery·2026
Same author

Big Data Approach to Assessment of an Aldosterone-Renin Ratio for Detection of Potential Surgical Cases of Primary Aldosteronism.

Hypertension (Dallas, Tex. : 1979)·2026
Same author

Seated Saline Suppression Test for Lateralizing Primary Aldosteronism.

Hypertension (Dallas, Tex. : 1979)·2026
Same author

Outcomes After Unilateral Adrenalectomy in Asymmetrical Bilateral Primary Aldosteronism.

Hypertension (Dallas, Tex. : 1979)·2025
Same author

Confirmatory Testing for Primary Aldosteronism : A Study of Diagnostic Test Accuracy.

Annals of internal medicine·2025
Same author

Bone in Parathyroid Diseases Revisited: Evidence From Epidemiological, Surgical and New Drug Outcomes.

Endocrine reviews·2025

Related Experiment Video

Updated: Jun 21, 2026

Laparoscopy-endoscopy Cooperative Surgery for the Treatment of Gastric Gastrointestinal Stromal Tumors
05:16

Laparoscopy-endoscopy Cooperative Surgery for the Treatment of Gastric Gastrointestinal Stromal Tumors

Published on: February 19, 2022

Gastrinomas: a historical perspective.

Meei J Yeung1, Janice L Pasieka

  • 1Department of Surgery, Monash University Endocrine Surgery Unit, Alfred Hospital, Melbourne, Australia.

Journal of Surgical Oncology
|August 5, 2009
PubMed
Summary

This paper traces the historical evolution of gastrinomas (tumors causing Zollinger-Ellison syndrome), from their 1955 discovery to modern diagnostic and treatment advancements.

Area of Science:

  • Endocrinology
  • Surgical Oncology
  • Medical History

Background:

  • The Zollinger-Ellison syndrome, characterized by gastrinomas, was first described in 1955.
  • Understanding gastrinomas has evolved significantly since their initial discovery.

Observation:

  • The diagnosis and management of gastrinomas have advanced alongside medical progress.
  • Diagnostic tools and medical treatments have increasingly impacted this surgical pathology.

Findings:

  • This review presents a historical perspective on the discovery and evolution of gastrinoma management.
  • The surgical treatment of gastrinomas has seen substantial development over the past five decades.

Implications:

  • Understanding the historical trajectory of gastrinoma management provides context for current practices.

Related Experiment Videos

Last Updated: Jun 21, 2026

Laparoscopy-endoscopy Cooperative Surgery for the Treatment of Gastric Gastrointestinal Stromal Tumors
05:16

Laparoscopy-endoscopy Cooperative Surgery for the Treatment of Gastric Gastrointestinal Stromal Tumors

Published on: February 19, 2022

  • This historical overview highlights the interplay between diagnostic innovation and therapeutic strategies in endocrinology.