Lef-1 isoforms regulate different target genes and reduce cellular adhesion.

Sarah Jesse1, Alexander Koenig, Volker Ellenrieder

  • 1Department of Internal Medicine I, University of Ulm, D-89081 Ulm, Germany.

Summary

Lymphoid enhancer factor 1 (Lef-1) isoforms in pancreatic cancer influence cell behavior. Lef-1 Deltaexon VI promotes migration, while Lef-1 FL enhances proliferation.

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