Related Experiment Video
Updated: Jun 21, 2026

Electromagnetic Source Imaging in Presurgical Evaluation of Children with Drug-Resistant Epilepsy
Published on: September 20, 2024
Hyperekplexia (startle disease) mimicking neonatal seizures: report of one case
Chao-Huei Chen1, Hsiu-Fen Lee, Ching-Shiang Chi
1Department of Pediatrics, Taichung Veterans General Hospital, Taichung, Taiwan. joy1477@gmail.com
Abstract:
Herein we report a case of a male infant with hyperekplexia. He was born after an uneventful pregnancy to healthy unrelated parents. At 2 days, he began to have frequent episodes of apnea accompanied with generalized tonic posture. Phenobarbital had been prescribed for the suspicion of neonatal seizures. However, the attack frequency remained the same. Clonazepam and clobazam were prescribed under the impression of hyperekplexia after the infant reached one month, and the apnea attacks quickly decreased. The startle reaction to tapping of the nasal bridge persisted at the age of 2 years. His growth and development were compatible with his age. A timely diagnosis in cases of hyperekplexia is crucial because affected neonates are at risk of sudden death from apnea.
More Related Videos
Related Concept Videos
Seizures: Classification
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
Epilepsy ll: Types
Seizures l: Introduction
Seizures ll: Types
Epilepsy and Seizures: Overview
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
REM Sleep Behavior Disorder
RBD is significantly associated with...

