[Clinico-economical aspects of long-term therapy with moditen-depot]

As many as 16 patients with multi-attack schizophrenia were examined for the dynamics of the efficacy of long-term therapy with moditen-depot , expressed in the clinico-economic parameters. It turned out that the degree of positive treatment effect was different, being dependent on the main disease tendencies during the treatment. In half patients who received the drug during retention of progredient tendencies, "depletion" of the positive treatment effect was observed which affected the dynamics of the clinico-economic parameters. Apparently, in the latter cases the replacement of the long-acting drug is desirable.