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Updated: Jun 21, 2026

Primary Culture of Dental Pulp Stem Cells
Published on: May 5, 2023
Dental stem cells for tooth regeneration and repair
1Guy's Hospital, Dental Institute, Kings College London, Department of Craniofacial Development, London SE1 9RT, UK.
Abstract:
Mesenchymal stem cells (MSCs) resident in bone marrow are one of the most studied and clinically important populations of adult stem cells. Cells with, similar properties to these MSCs have been described in several different tooth tissues and the potential ease with which these dental MSCs could be obtained from patients has prompted great interest in these cells as a source of MSCs for cell-based therapeutics. In this review we address the current state of knowledge regarding these cells, their properties, origins, locations, functions and potential uses in tooth tissue engineering and repair. We discuss some of the key controversies and outstanding issues, not least of which whether dental stem cells actually exist.
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