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Updated: Jun 21, 2026

Quantitative Measurement of Intrathecally Synthesized Proteins in Mice
Published on: November 29, 2019
Reference values for serum proteins of common laboratory rodent strains
Julia Zaias1, Martha Mineau, Carolyn Cray
1Division of Veterinary Resources, University of Miami Miller School of Medicine, Miami, Florida; Division of Comparative Pathology, University of Miami Miller School of Medicine, Miami, Florida. jzaias@med.miami.edu
Abstract:
Protein electrophoresis is a common proven technique to determine the protein components of plasma or serum in human, veterinary, and laboratory animal medicine. Changes in albumin and globulin protein levels can provide early and valuable diagnostic and prognostic information. Here we describe a preliminary analysis of the distribution of serum protein fractions in adult BALB/c, C57BL/6, and CD1 mice and Sprague-Dawley rats and describe the changes in protein values from birth to maturity in BALB/c mice and Sprague-Dawley rats. Quantifiable changes in the electrophoretic profile were apparent in mice with chronic-active dermatitis.

