Related Experiment Video
Updated: Jun 21, 2026
Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
Anterior segment optical coherence tomography for transepithelial phototherapeutic keratectomy in central corneal
Joseph J K Ma1, Santos S Tseng, Blake A Yarascavitch
1Department of Ophthalmology and Visual Sciences, Faculty of Science, University of Toronto, Ontario, Canada. joseph.ma@utoronto.ca
Purpose:
To demonstrate the use of anterior segment optical coherence tomography (ASOCT) in planning phototherapeutic keratectomy (PTK) removal of central corneal stromal scarring.
Methods:
A 62-year-old male presented with central corneal scars associated with significant ocular surface disease. Videokeratographies obtained using 3 different systems were not reliable. ASOCT, however, provided consistent pachymetry in the presence of noncalcific stromal opacity, which extended below Bowman membrane. PTK was performed with a transepithelial ablation, mitomycin C (MMC), and a slightly myopic photorefractive keratectomy.
Results:
Slit-lamp examination and postoperative ASOCT revealed an optically clear cornea with no evidence of stromal haze at any time point.
Conclusion:
Transepithelial PTK guided by ASOCT can allow for the precise and accurate removal of central corneal stromal opacities, resulting in a favorable refractive outcome.
