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Updated: Jun 21, 2026

A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis
Published on: May 14, 2013
Histopathologic description of Wingspan stent in acute ischemic stroke
Vivien H Lee1, Susan Samuels, Thomas J Herbst
1Department of Neurological Sciences, Rush University Medical Center, 1725 W. Harrison Street #1121, Chicago, IL 60612, USA. vivien_lee@rush.edu
Objective And Importance:
We report the histopathologic examination of Wingspan stent in acute ischemic stroke.
Clinical Presentation:
A 75-year-old female presented with acute left-hemiplegia due to right carotid terminus occlusion. Mechanical embolectomy was unsuccessful.
Intervention:
A Wingspan stent was placed from the distal intracranial carotid artery to the proximal middle cerebral artery stem and established partial antegrade flow. The patient died of malignant infarction on post-stroke day 7. At autopsy, embolized calcified atherosclerotic plaque fragments were noted within a non-occlusive thrombus over which the Wingspan stent was deployed. There was no evidence of intimal or media dissection or perforator ostium occlusion.
Conclusion:
Our case provides a rare pathological description of intracranial stent placement in the setting of acute ischemic stroke.
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