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Updated: Jun 21, 2026

Preterm EEG: A Multimodal Neurophysiological Protocol
Published on: February 18, 2012
[Assessment of preterm children's early development]
Cibelle Kayenne Martins Roberto Formiga1, Maria Beatriz Martins Linhares
1Programa de Pós-graduação em Saúde Mental da Faculdade de Medicina de Ribeirão da Universidade de São Paulo, Ribeirão Preto, SP, Brasil. cibellekayenne@gmail.com
Insights
Children born preterm face developmental challenges. Key predictors of development at two years include neonatal risks, low birth weight, and cerebral injuries.
Area of Science:
- Neonatal care
- Developmental pediatrics
- Perinatal medicine
Background:
- Preterm birth significantly impacts child development.
- Numerous risk factors influence developmental trajectories.
- Evaluating preterm infants requires understanding these factors.
Purpose of the Study:
- To systematically review literature on preterm infant development up to 24 months.
- To identify key biological risk factors and their impact.
- To determine predictors of developmental outcomes at two years.
Main Methods:
- Systematic literature review from 2000-2005.
- Focused on developmental evaluations of preterm infants up to 24 months corrected age.
- Analyzed biological risk factors and developmental outcomes.
Main Results:
- Intraventricular hemorrhage, necrotizing enterocolitis, chronic pulmonary disease, and intrauterine growth retardation were prominent risks.
- Motor development was the most frequently assessed area.
- Early evaluations often occurred within the first six months of life.
Conclusions:
- Neonatal risks, low birth weight, male sex, cerebral injuries, and abnormal early movements predict two-year development.
- Early identification of risk factors is crucial for intervention.
- Continued monitoring of preterm infants is essential for optimal outcomes.
Abstract:
Preterm birth is an event that affects the child's healthy development. Several studies have addressed the evaluation of children born preterm and the influence that multiple risk factors have on the course of their development. This study performed a systematic review of the literature from 2000 to 2005 about the evaluation of the development of children born preterm until the age of 24 months. The biological risk factors were present in every study, with highlights on intraventricular hemorrhage, necrotizing enterocolitis, chronic pulmonary disease, and retardation of intrauterine development as the most studied risks. The child's motor development was the most studied area. In terms of age, the first evaluations focused on the first six months of life. Neonatal risk, low birth weight, baby boys, cerebral injuries, and first-week abnormal spontaneous movements were predicting factors of preterm child development at the age of two years.
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