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Updated: Jun 21, 2026

Generation of a Rat Model of Acute Liver Failure by Combining 70% Partial Hepatectomy and Acetaminophen
Published on: November 27, 2019
Implication of normal liver enzymes in liver disease
Vincenza Calvaruso1, Antonio Craxì
1Gastroenterologia & Epatologia, DIBIMIS, Università di Palermo, 90127 Palermo, Italy. vcalvaruso@libero.it
Abstract:
Chronic liver disease is usually asymptomatic until its late stages and also significant hepatic necroinflammation and fibrosis may be present in persistently normal ALT levels HBV, HCV carriers or similarly, in patients with nonalcoholic fatty liver disease. Given the large number of persons in the general population which may harbor a clinically significant liver disease behind the screen of normal alanine aminotransferase, more attention should be devoted to future research for alternative noninvasive markers of liver damage.
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