Related Experiment Video

Updated: Jun 21, 2026

Cefoperazone-treated Mouse Model of Clinically-relevant Clostridium difficile Strain R20291
06:51

Cefoperazone-treated Mouse Model of Clinically-relevant Clostridium difficile Strain R20291

Published on: December 10, 2016

Clinically important interaction between statin drugs and Clostridium difficile toxin?

Timothy McGuire1, Paul Dobesh, Don Klepser

  • 1College of Pharmacy, University of Nebraska Medical Center, Omaha, NE 68198-6045, United States. trmcguir@unmc.edu

Medical Hypotheses
|August 7, 2009
PubMed
Summary

Statins may increase the risk of Clostridium difficile associated disease (CDAD). This study suggests statins potentiate C. difficile toxins, leading to a higher incidence and severity of CDAD.

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