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Related Concept Videos

Computed Tomography01:10

Computed Tomography

Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
Imaging Studies III: Computed Tomography01:27

Imaging Studies III: Computed Tomography

DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

Radiological Investigation III: Pulmonary Angiogram and PET Scan

Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
Imaging Studies II: Positron Emission Tomography and Scintigraphy01:25

Imaging Studies II: Positron Emission Tomography and Scintigraphy

Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET

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Related Experiment Video

Updated: Jun 21, 2026

Clinical Imaging of Microwave Mammography
05:28

Clinical Imaging of Microwave Mammography

Published on: November 14, 2025

Breast tomosynthesis in clinical practice: initial results.

Hendrik J Teertstra1, Claudette E Loo, Maurice A A J van den Bosch

  • 1Division of Radiology, The Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands. h.teertstra@nki.nl

European Radiology
|August 7, 2009
PubMed
Summary

Digital breast tomosynthesis (DBT) shows potential value in detecting breast cancer in women with abnormal screening mammograms or symptoms. While DBT and mammography have similar cancer detection rates, DBT can aid in diagnosis when mammography is inconclusive.

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Area of Science:

  • Medical Imaging
  • Radiology
  • Oncology

Background:

  • Mammography is a standard screening tool for breast cancer.
  • Clinical symptoms or abnormal screening mammograms warrant further investigation.
  • Digital breast tomosynthesis (DBT) offers a 3D view of breast tissue.

Purpose of the Study:

  • To evaluate the diagnostic value of tomosynthesis compared to mammography.
  • To assess tomosynthesis's utility in women with abnormal screening mammograms or clinical symptoms.
  • To calculate the sensitivity and specificity of both imaging techniques for cancer detection.

Main Methods:

  • A prospective study involving 513 women with abnormal screening mammograms or symptoms.
  • Both mammography and tomosynthesis were performed and classified using ACR BI-RADS criteria.
  • Sensitivity and specificity for cancer detection were calculated for each modality.

Main Results:

  • In 112 newly detected cancers, both mammography and tomosynthesis were false-negative in 8 cases (7%).
  • Combining mammography and tomosynthesis detected 109 cancers; both missed 3 carcinomas.
  • Sensitivity for breast cancer detection was 92.9% for both techniques; specificity was 86.1% for mammography and 84.4% for tomosynthesis.

Conclusions:

  • Tomosynthesis can serve as an adjunct to mammography for women with abnormal screening or symptoms.
  • Lesions detected by tomosynthesis may also be identified through other clinical work-up methods.
  • DBT demonstrates comparable sensitivity to mammography in this patient cohort.