Related Experiment Video
Updated: Jun 21, 2026

Iris Fixation via External Pentagram Suturing
Published on: May 5, 2022
[Iridoschisis associated to congenital syphilis: serological confirmation at the 80's]
G Pérez-Carro1, M Vilanova, M G Antuña
1Servicio de Oftalmología, Hospital del Valle del Nalón, Asturias, España. gemurri27@yahoo.es
Clinical Case:
Female in her eighties is admitted suffering from unilateral ocular pain. On examination we observed, as well as corneal abrasion, a bilateral iridoschisis with a frayed iris, unfolded between its stromal layers.
Discussion:
This rare case is related either to senile degenerative change or to angle-closure glaucoma. However, it is also associated with congenital syphilis with or without the presence of interstitial keratitis. Infant conjunctivitis and a "salt and pepper" appearance of the fundus oculi complete the diagnosis. It is confirmed that the patient had suffered from congenital late syphilis, cured by the age of 80: this confirmation is reached by treponemal (RPR-) and non-treponemal (TPHA+) serological tests.
