Related Experiment Video
Updated: Jun 21, 2026
A New Technique for Treating Low-risk Prostate Cancer—Super Active Surveillance
Published on: November 7, 2025
Surveillance following orchiectomy for stage I testicular seminoma: long-term outcome
Takahiro Yoshida1, Ken-ichi Kakimoto, Kentaro Takezawa
1Department of Urology, Osaka Medical Center for Cancer and Cardiovascular diseases, Osaka City, Osaka, Japan. takahiro-y@sannet.ne.jp
Objectives:
To report the long-term outcome of surveillance for stage I seminoma at a single institution in Japan.
Methods:
A retrospective review of medical records of 64 patients who underwent orchiectomy between January 1982 and December 2005 was carried out. All of them were managed by surveillance for stage I seminoma.
Results:
Median follow-up time was 123.8 months. Of the 64 patients, seven developed relapse. Four relapses occurred within the first year after orchiectomy, but three occurred over 4 years after orchiectomy. The actuarial relapse-free rates at 5, 10, and 15 years were 92.1%, 90.0%, and 86.0%, respectively. All patients received salvage chemotherapy at relapse. Four of these seven patients were alive without evidence of disease. One patient died of seminoma and one was alive with this disease. The remaining one patient died of leukemia without secondary relapse of seminoma. T classification was a statistically significant (P = 0.028) risk factor for relapse on univariate analysis. In T1 patients, relapse-free rates at 5, 10, and 15 years were all 97.1%, whereas in T2/T3 patients the corresponding relapse-free rates were 86.4%, 82.1%, and 71.8%, respectively.
Conclusions:
The relapse-free rate in the present study was similar to previous reports. Late relapse should be considered during surveillance.
