Related Experiment Video
Updated: Jun 21, 2026

Oral Combinational Antiretroviral Treatment in HIV-1 Infected Humanized Mice
Published on: October 6, 2022
Smoking cessation in HIV patients: rate of success and associated factors
M Fuster1, V Estrada, M C Fernandez-Pinilla
1Internal Medicine/HIV Unit, Hospital Clínico San Carlos, Madrid, Spain. mfuster.hcsc@salud.madrid.org
Insights
Smoking cessation in HIV patients is challenging, with 25% quitting after 12 months. Higher patient motivation significantly impacts successful smoking cessation and reduces cardiovascular risk.
Area of Science:
- Cardiology
- Infectious Diseases
- Public Health
Background:
- Smoking is a primary modifiable risk factor for cardiovascular disease.
- HIV-infected individuals exhibit double the smoking prevalence compared to the general population.
Purpose of the Study:
- To determine the 12-month smoking cessation success rate in HIV patients.
- To identify factors associated with smoking cessation success.
- To characterize tobacco consumption and nicotine dependence in this population.
Main Methods:
- A longitudinal descriptive study involving 368 HIV-infected patients.
- Smokers in the action stage initiated a smoking cessation program.
- Data collected on tobacco consumption and cessation success.
Main Results:
- 63.9% of HIV patients were active smokers; 14% entered a cessation program.
- The 12-month smoking cessation rate was 25%.
- Higher motivation (P=0.048) and reduced cardiovascular risk (P=0.026) were observed in successful quitters.
Conclusions:
- High smoking prevalence (63.9%) exists among HIV patients.
- Low uptake (14%) of smoking cessation programs was observed.
- Patient motivation is the key factor for successful smoking cessation (25% at 12 months).
Background:
Smoking is the modifiable cardiovascular (CV) risk factor that contributes most to causing premature CV disease. Prevalence of smoking in patients with HIV infection is double that of the general population.
Objectives:
To determine the rate of patients succeeding in quitting smoking after 12 months, factors associated with this success, and the characteristics of tobacco consumption and nicotine dependence.
Methods:
Longitudinal descriptive study. Three hundred and sixty-eight HIV-infected patients were interviewed. Smokers in Prochaska's stage of action began a programme to quit smoking. We registered the variables related to tobacco consumption and the level of success of cessation.
Results:
63.9% of the patients were active smokers and 14% of them began the cessation programme. Average motivation for cessation was 7.8 +/- 1.4 (Richmond) and nicotine dependence rate 5.5 +/- 3.0 (Fagerström). After 1 year, 25% had quit smoking. Those patients who stopped smoking presented a higher motivation level (8.8 +/- 1.3 vs. 7.5 +/- 1.5, P=0.048). Cessation significantly reduced their CV risk at 12 months [2.5 [interquartile range (IQR) 2.0-5.2] vs. 1.7 [IQR 1.0-3.5], P=0.026].
Conclusions:
The prevalence of smokers in our population of HIV-infected patients was 63.9%. Only 14% began a smoking cessation programme. Twelve months after a programme to quit smoking, cessation rate was 25%; this was influenced mostly by the level of motivation of the patient.
Related Concept Videos
Retrovirus Life Cycles
Pulmonary Tuberculosis I
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Chronic Obstructive Pulmonary Disease-V: Management
Smoking Cessation
Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies
Medical History
Sexually Transmitted Infections
Stress Prevention and Stress Management Techniques IV

