Related Experiment Video

Updated: Jun 21, 2026

A Protocol to Set Up Needle-Free Connector with Positive Displacement on Central Venous Catheter in Intensive Care Unit
09:57

A Protocol to Set Up Needle-Free Connector with Positive Displacement on Central Venous Catheter in Intensive Care Unit

Published on: July 13, 2019

Intravenous peripherally-inserted central catheters for antibiotic therapy in children with cystic fibrosis

S Bui1, F Babre, S Hauchecorne

  • 1CHU de Bordeaux, Hôpital Pellegrin-Enfants, CRCM Pédiatrique, France. stephanie.bui@chu-bordeaux.fr

Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society
|August 8, 2009
PubMed

Insights

Peripherally inserted central catheters (PICCs) are safe and effective for delivering intravenous therapy in children with cystic fibrosis (CF). This study found high success rates, minimal complications, and improved patient well-being with PICC use.

Area of Science:

  • Pediatric Medicine
  • Vascular Access Devices
  • Cystic Fibrosis Management

Background:

  • Cystic Fibrosis (CF) requires frequent intravenous (IV) therapy.
  • Central venous access is crucial for effective CF treatment.
  • Peripherally inserted central catheters (PICCs) offer a potential solution for venous access in pediatric CF patients.

Purpose of the Study:

  • To evaluate the safety and efficacy of peripherally inserted central catheters (PICCs) in children with cystic fibrosis.
  • To assess the procedural success rate, complications, and patient/operator satisfaction associated with PICC insertion in this population.

Main Methods:

  • A descriptive study involving the insertion of PICCs in pediatric patients with CF.
  • Data collected included insertion success rates, procedure duration, difficulties encountered, and side effects.
  • Patient and operator satisfaction, catheter functionality, and central vein patency were also assessed.

Main Results:

  • PICC insertion was successful in 93.2% of 44 procedures across 24 children (median age 10.2 years).
  • Few procedural difficulties and no major complications or infections were observed.
  • Catheters remained functional for IV therapy in most cases, with high operator and patient satisfaction.

Conclusions:

  • Peripherally inserted central catheters (PICCs) are a safe, well-tolerated, and effective option for IV therapy in pediatric CF patients.
  • PICC insertion can be performed easily in a ward setting, potentially improving patient comfort and well-being.
  • PICCs demonstrate high functionality and lead to positive outcomes in children with cystic fibrosis requiring long-term venous access.
Abstract

More Related Videos

Hickman Catheter Use for Long-Term Vascular Access in a Preclinical Swine Model08:51

Hickman Catheter Use for Long-Term Vascular Access in a Preclinical Swine Model

Published on: March 31, 2023

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings06:59

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings

Published on: November 9, 2016

Related Concept Videos

Parentral Nutrition: Centeral and Peripheral Parental Nutrition01:27

Parentral Nutrition: Centeral and Peripheral Parental Nutrition

Parenteral Nutrition (PN) delivers essential nutrients directly into the bloodstream, bypassing the digestive system. It is commonly used for individuals with severe digestive disorders or conditions that prevent normal nutrient absorption.
PN can be administered through two primary routes:
1. Central Parenteral Nutrition (CPN):
CPN involves delivering a high concentration of nutrients through a large vein. This is typically achieved using a Peripherally Inserted Central Catheter (PICC) or,...
Endocarditis IV: Nursing Management01:29

Endocarditis IV: Nursing Management

Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...
Cystic Fibrosis: Management01:24

Cystic Fibrosis: Management

Cystic fibrosis (CF) is an autosomal recessive disorder that predominantly affects individuals of Northern European descent, occurring at a rate of 1 in 3500. It is caused by a genetic mutation in a gene on chromosome 7, most commonly the ΔF508 mutation, that codes for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. This results in thicker mucus secretions and obstruction pathologies in multiple organs, including the lungs and sinuses.
Sinus disease and chronic sinusitis...
Extracorporeal Removal of Drugs: Continuous Renal Replacement Therapy01:26

Extracorporeal Removal of Drugs: Continuous Renal Replacement Therapy

Continuous Renal Replacement Therapy (CRRT) is an essential intervention for patients experiencing severe kidney dysfunction. This therapy offers a continuous mechanism for removing fluids and toxins from the bloodstream, leveraging the patient’s blood pressure to facilitate filtration through a specialized filter. This method contrasts with intermittent dialysis, providing a gentler and more consistent removal of waste products and excess fluid, which is particularly beneficial in critically...
Hemodialysis I: Introduction01:25

Hemodialysis I: Introduction

Hemodialysis (HD) is a medical treatment that artificially removes waste products, excess fluids, and toxins from the blood when the kidneys are no longer able to perform these functions effectively. In this process, blood is filtered through a semipermeable membrane, allowing for the selective removal of waste while preserving necessary components like blood cells and proteins. Hemodialysis is typically performed in patients with end-stage renal disease (ESRD) or severe kidney...