Related Experiment Video
Updated: Jun 21, 2026

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
Published on: February 6, 2021
Burkholderia cepacia keratitis with endophthalmitis
Kemal Örnek1, Mehmet Özdemir1, Ahmet Ergin1
1Department of Ophthalmology, School of Medicine, Kirikkale University, Kirikkale, Turkey.
Abstract:
Keratitis with endophthalmitis of the right eye occurred in a 78-year-female following a complicated cataract surgery. Prompt intravitreal vancomycin and ceftazidime with topical fortified tobramycin and cefazolin treatments were started. The corneal, aqueous and vitreous cultures grew a Burkholderia cepacia complex (Bcc) strain on the fourth day. Restriction fragment length polymorphism analysis of the recA amplicon revealed B. cepacia genomovar I. The organism was found to be susceptible to ceftazidime, ciprofloxacin and ofloxacin. Topical ciprofloxacin was given immediately. At day 10, the pain relieved and the clinical condition of the patient improved with resolution of the purulent discharge, severe circumcorneal congestion and chemosis. The size of the corneal abscess and anterior chamber exudation decreased. The Bcc should be included among the bacterial species that may cause keratitis following intraocular surgeries.
Related Concept Videos
Glaucoma: Overview
Endocarditis I: Introduction
Angle Closure Glaucoma: Treatment
Microbiome of the Eye
Bacterial Meningitis II: Pathophysiology
Cryptococcal Meningitis

