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Updated: Jun 21, 2026

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
Published on: June 13, 2021
Impact of antenatal and postpartum maternal mental illness: how are the children?
Sarah R Brand1, Patricia A Brennan
1Department of Clinical Psychology, Emory University, 1462 Clifton Road, Atlanta, GA, USA. sbrand@emory.edu
Abstract:
Prospective studies that begin during pregnancy and follow the mothers and children into adolescence have shown that maternal mental illness during the antenatal and postpartum period can have long-lasting negative consequences on the developing child. The findings from these prospective studies and a discussion of the consistencies and inconsistencies in the current literature are presented. The effects of maternal anxiety and depression during the perinatal period on cognitive, behavioral, and psychologic development from infancy through adolescence are examined.
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