Related Experiment Video
Updated: Jun 21, 2026
08:29
Generation of Cationic Nanoliposomes for the Efficient Delivery of In Vitro Transcribed Messenger RNA
Published on: February 1, 2019
Characterization of liposomes for cancer cell transfection
Svetlana A Tatarkova1, Satvinder Khaira
1Department of Physics, Durham University, South Road, Durham, DH1 3LE, UK.
The Open Biomedical Engineering Journal
|August 8, 2009
Abstract:
We have characterized a broad range of liposome formulations with varying DcChol:DOPE ratio. Subsequent addition of DcChol to liposomes increases its positive surface charge. However, loading the nuclear acids did not neutralize the overall negative surface potential to a similar extent. The liposomes were tested by transfection of DNA in living cancer cells.
