Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Microbial Biosensors01:17

Microbial Biosensors

Microbial biosensors are analytical devices that utilize living microbes to detect specific substances through measurable signals. These devices consist of two main components: biosensing organisms and signal-transducing elements. Biosensing organisms, such as Escherichia coli or Saccharomyces cerevisiae, are typically housed in multiwell plates connected to transducers, enabling rapid, real-time detection of target analytes.Signal Generation MechanismWhen a target analyte—such as...
Automated Microbial Diagnostics01:24

Automated Microbial Diagnostics

Automated diagnostic analyzers have transformed clinical microbiology by providing rapid and reliable methods for pathogen identification and antibiotic susceptibility testing. Among these systems, the Vitek 2 is widely used because it automates the traditionally labor-intensive processes of microbial identification (ID) and antibiotic susceptibility testing (AST), delivering standardized and timely results that are essential for effective patient care.Microbial Identification with ID CardsThe...
Chemical Agents for Microbial Control01:27

Chemical Agents for Microbial Control

Chemicals play important roles in controlling microbial growth by targeting microbial structures and functions as sanitizers, antiseptics, disinfectants, and sterilants.Alcohols are commonly used sanitizers, effectively disrupting lipid membranes, which compromises cell integrity. They are also used as antiseptics and disinfectants due to their rapid action and versatility.Phenols and their derivatives phenolics , known for denaturing proteins and disrupting cell membranes, are particularly...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

CanCHD Study of Hematopoietic Cancers in Children With and Without Genetic Syndromes.

Journal of the American Heart Association·2023
Same author

A key protein from <i>Borrelia burgdorferi</i> could stimulate cytokines in human microglial cells and inhibitory effects of Cucurbitacin IIa.

IBRO neuroscience reports·2023
Same author

Flow diverters versus stent-assisted coiling in unruptured intracranial vertebral artery dissecting aneurysms.

Journal of neurosurgery·2023
Same author

Variational perturbation theory for dynamic polarizabilities and dispersion coefficients.

Physical review. E·2023
Same author

Stent-assisted coiling of intracranial carotid ophthalmic segment aneurysm segment aneurysms: Long-term follow-up from a single center.

Journal of interventional medicine·2023
Same author

A deep learning framework for intracranial aneurysms automatic segmentation and detection on magnetic resonance T1 images.

European radiology·2023

Related Experiment Video

Updated: Jun 21, 2026

Ultrasensitive Detection of Biomarkers by Using a Molecular Imprinting Based Capacitive Biosensor
08:22

Ultrasensitive Detection of Biomarkers by Using a Molecular Imprinting Based Capacitive Biosensor

Published on: February 16, 2018

Virus-based chemical and biological sensing.

Chuanbin Mao1, Aihua Liu, Binrui Cao

  • 1Department of Chemistry & Biochemistry, University of Oklahoma, Norman, OK 73019, USA. cbmao@ou.edu

Angewandte Chemie (International Ed. in English)
|August 8, 2009
PubMed
Summary

Viruses, particularly bacteriophages, are emerging as highly selective biosensors for detecting various analytes. Their stability and adaptability with nanomaterials enhance their application in chemical and biological sensing technologies.

More Related Videos

Using Synthetic Biology to Engineer Living Cells That Interface with Programmable Materials
10:28

Using Synthetic Biology to Engineer Living Cells That Interface with Programmable Materials

Published on: March 9, 2017

Engineering Antiviral Agents via Surface Plasmon Resonance
13:00

Engineering Antiviral Agents via Surface Plasmon Resonance

Published on: June 14, 2022

Related Experiment Videos

Last Updated: Jun 21, 2026

Ultrasensitive Detection of Biomarkers by Using a Molecular Imprinting Based Capacitive Biosensor
08:22

Ultrasensitive Detection of Biomarkers by Using a Molecular Imprinting Based Capacitive Biosensor

Published on: February 16, 2018

Using Synthetic Biology to Engineer Living Cells That Interface with Programmable Materials
10:28

Using Synthetic Biology to Engineer Living Cells That Interface with Programmable Materials

Published on: March 9, 2017

Engineering Antiviral Agents via Surface Plasmon Resonance
13:00

Engineering Antiviral Agents via Surface Plasmon Resonance

Published on: June 14, 2022

Area of Science:

  • Biotechnology
  • Nanotechnology
  • Analytical Chemistry

Background:

  • Viruses exhibit high selectivity and sensitivity for detecting diverse analytes like explosives, proteins, and toxins.
  • Bacteriophages (phages) are extensively studied due to their specific bacterial infection capabilities and stability.
  • Phages can be integrated with nanomaterials and immobilized on transducers for advanced sensing devices.

Purpose of the Study:

  • To review the advancements in utilizing phages for chemical and biological sensing.
  • To highlight the integration of phages with traditional analytical techniques.
  • To discuss the role of virus-nanomaterial composites in sensing applications.

Main Methods:

  • Phage display technique for identifying target-specific nonlytic phages and their peptides/proteins.
  • Utilizing lytic phages to release intracellular marker molecules for assaying.
  • Conjugation of phages with nanomaterials for enhanced sensor performance.
  • Immobilization of phages onto transducer surfaces within analytical devices.

Main Results:

  • Phages offer high selectivity and sensitivity in detecting a wide range of target analytes.
  • Both nonlytic and lytic phages provide distinct advantages for biosensing.
  • Virus-nanomaterial composites demonstrate significant potential in sensing applications.
  • Phages are stable and amenable to integration into various analytical platforms.

Conclusions:

  • Phages represent a versatile and powerful tool for developing advanced chemical and biological sensors.
  • The combination of phages with nanomaterials and traditional analytical techniques opens new avenues in detection technologies.
  • Further research into virus-based sensors promises enhanced sensitivity, selectivity, and stability for analyte detection.