A chemistry cascade: from physical organic studies of alkoxy radicals to alkaloid synthesis

Albert Padwa1

  • 1Department of Chemistry, Emory University, Atlanta Georgia 30322, USA. chemap@emory.edu

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The reaction of hydrogen bromide with alkenes in the presence of hydroperoxides or peroxides proceeds via anti-Markovnikov addition. The radical chain reaction comprises initiation, propagation, and termination steps.
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Radical Substitution: Allylic Bromination

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