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Updated: Jun 21, 2026
09:21
Tumorsphere Derivation and Treatment from Primary Tumor Cells Isolated from Mouse Rhabdomyosarcomas
Published on: September 13, 2019
A case of botryoid-type embryonal rhabdomyosarcoma
1Department of Dermatology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea. miumiu@www.amc.seoul.kr
Clinical and Experimental Dermatology
|August 12, 2009
Summary
This case study highlights botryoid-type embryonal rhabdomyosarcoma in an infant, a rare anal mass. Early biopsy is crucial for accurate diagnosis and improved prognosis of this rhabdomyosarcoma subtype.
Area of Science:
- Pediatric Oncology
- Surgical Pathology
Background:
- Congenital anal masses require careful differential diagnosis.
- Embryonal rhabdomyosarcoma is a rare pediatric malignancy.
- The botryoid subtype can present with deceptively benign features.
Observation:
- An infant presented with a congenital polypoid anal mass.
- Histological examination revealed a myxoma-like appearance.
- Cells showed features suggestive of rhabdomyoblasts with eosinophilic cytoplasm.
Findings:
- Immunohistochemistry confirmed tumor cells were strongly desmin-positive.
- Myoglobin immunoreactivity was observed in 10% of tumor cells.
- Diagnosis was confirmed as botryoid-type embryonal rhabdomyosarcoma.
Implications:
- Botryoid-type embryonal rhabdomyosarcoma can exhibit benign clinical and histological characteristics.
- Early biopsy is essential for accurate diagnosis and improved patient outcomes.
- This case underscores the importance of thorough histopathological evaluation for congenital anal masses.
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