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Updated: Jun 21, 2026

Cell-Specific Paired Interrogation of the Mouse Ovarian Epigenome and Transcriptome
Published on: February 24, 2023
Genetic and genomic insights into age at natural menopause
Francisco Jesus Moron1, Agustin Ruiz, Jose Jorge Galan
1Department of Structural Genomics, Neocodex SL, Avda, Charles Darwin 6, Acceso A, Isla de la Cartuja, 41092, Sevilla, Spain.
Abstract:
The age at natural menopause shows great variability. It has been proposed that early age at menopause is a risk factor for osteoporosis and cardiovascular disease, whereas later age at menopause is a risk factor for breast cancer. In addition, it is thought that the genetic factors accounting for the genetic variability in age at menopause could also play a role in those diseases, as well as infertility in women. In this minireview we comment on the latest genetics and genomics insights into age at natural menopause.
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