Clusterin regulates transthyretin amyloidosis

Ko-Woon Lee1, Dong-Hoon Lee, Hosun Son

  • 1Department of Anatomy and Neurobiology, Institute of Health Sciences, College of Medicine, Gyeongsang National University, Gyeongnam 660-751, South Korea.

Summary

Clusterin protein inhibits transthyretin (TTR) amyloidosis by stabilizing TTR structure. This finding offers a potential new therapeutic strategy for treating TTR amyloidosis diseases like FAP.

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