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Updated: Jun 21, 2026

Intravenous and Intra-amniotic In Utero Transplantation in the Murine Model
Published on: October 9, 2018
Amniovacucentesis vs standard syringe technique for amniocentesis: experience with 1219 cases
Pavel Calda1, Miroslav Brestak
1Department of Obstetrics and Gynecology, First Medical School, Charles University, Prague, Czech Republic. calda@gynstart.cz
Objective:
The aim of the study was to compare amniovacucentesis to the usual syringe use for amniotic fluid aspiration.
Study Design:
We compared 2 groups of procedures: 1117 amniocenteses performed with the usual syringe technique and 1219 amniovacucenteses.
Results:
The numbers of needle insertions, unsuccessful amniocyte cultures, and miscarriage up to 21 days after the procedure were statistically not significant (P>.01) comparing the 2 techniques.
Conclusion:
The vacuum tube serves as an automated aspiration tool alternative. The major subjective differences between the 2 methods are the operator's comfort and dexterity during sampling and the absence of an extra manipulation of the amniotic fluid after aspiration.
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