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Blood Transfusion01:15

Blood Transfusion

Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
Blood Transfusion and Agglutination02:45

Blood Transfusion and Agglutination

Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
Bone Marrow Sampling and Transplants01:22

Bone Marrow Sampling and Transplants

Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...

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Related Experiment Video

Updated: Jun 21, 2026

Reverse Total Shoulder Arthroplasty
10:10

Reverse Total Shoulder Arthroplasty

Published on: July 5, 2011

Predicting transfusion in shoulder arthroplasty.

Ross A Schumer1, Jonathan S Chae, Ronald J Markert

  • 1Department of Orthopaedic Surgery, Sports Medicine and Rehabilitation, Wright State Universty-Boonshoft School of Medicine, Dayton, OH, USA.

Journal of Shoulder and Elbow Surgery
|August 12, 2009
PubMed
Summary

Preoperative hemoglobin levels, age, and comorbidities predict transfusion needs in shoulder arthroplasty. A hemoglobin level below 12.5 g/dL indicates a higher risk, guiding safe blood management strategies.

Related Experiment Videos

Last Updated: Jun 21, 2026

Reverse Total Shoulder Arthroplasty
10:10

Reverse Total Shoulder Arthroplasty

Published on: July 5, 2011

Area of Science:

  • Orthopedic Surgery
  • Transfusion Medicine
  • Anesthesiology

Background:

  • Shoulder arthroplasty can necessitate blood transfusions.
  • Identifying patients at high risk for transfusion is crucial for effective blood management.
  • Preoperative optimization of blood management strategies is essential.

Purpose of the Study:

  • To evaluate the incidence of transfusion in shoulder arthroplasty.
  • To determine clinical factors associated with increased transfusion risk.
  • To develop an algorithm for preoperative blood management planning.

Main Methods:

  • A two-phase study involving 280 procedures for prediction rule development and 109 for validation.
  • Retrospective review identified risk factors, including a preoperative hemoglobin level < 12.5 g/dL.
  • Prospective application of the algorithm in a validation cohort.

Main Results:

  • The transfusion rate was 19.6% in the development phase.
  • Preoperative hemoglobin (< 12.5 g/dL), age, and comorbidity count were significant predictors.
  • A hemoglobin level < 12.5 g/dL indicated a 4-fold increased transfusion risk.

Conclusions:

  • Preoperative hemoglobin, age, and comorbidities predict transfusion requirements in shoulder arthroplasty.
  • Using a preoperative hemoglobin cutoff of 12.5 g/dL for blood ordering is safe and effective.
  • This approach aids in tailored preoperative blood management.