Related Experiment Video
Updated: Jun 21, 2026

A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis
Published on: May 14, 2013
Outcomes of angioplasty and stenting at the common carotid origin
Yasha Kadkhodayan1, Christopher J Moran, Colin P Derdeyn
1Interventional Neuroradiology, Mallinckrodt Institute of Radiology, St. Louis, MO 63110, USA.
Insights
Angioplasty and stenting effectively treat common carotid artery origin stenosis with low complication rates. This less invasive option shows promise compared to traditional bypass surgery.
Area of Science:
- Vascular Surgery
- Interventional Cardiology
- Neurology
Background:
- Conventional treatment for common carotid artery origin stenosis involves invasive bypass surgery.
- This study explores angioplasty and stenting as a less invasive alternative.
Purpose of the Study:
- To assess the procedural feasibility and safety of angioplasty and stenting for common carotid artery origin stenosis.
- To evaluate this less invasive approach compared to traditional open surgery.
Main Methods:
- Retrospective review of 8 angioplasty and/or stenting procedures in 7 patients with common carotid origin stenosis or dissection.
- Data collection included imaging reports and clinical follow-up, supplemented by telephone interviews.
- Procedural and midterm complication rates were calculated.
Main Results:
- 7 out of 8 procedures (87.5%) successfully resolved stenosis.
- No procedural strokes occurred (0%).
- Two transient ischemic attacks (TIAs) occurred (25%), with one recurrent TIA; no TIAs in asymptomatic patients.
Conclusions:
- Angioplasty and stenting are effective in treating common carotid artery origin stenosis.
- The procedure demonstrates low rates of ischemic complications, offering a viable less invasive option.
Background:
Conventional treatment of stenosis at the common carotid artery origin has involved extra-anatomic bypass using an open cervical approach or median sternotomy. The goal of this study is to determine the procedural feasibility and safety of angioplasty and stenting at the common carotid origin as a less invasive alternative.
Methods:
Between March 1996 and November 2005, a total of 248 carotid angioplasty and/or stenting procedures were performed at our institution. Of these, 8 procedures were performed in 7 patients for treatment of a stenosis or dissection located at the common carotid origin. There were 4 males and 3 females with a mean age of 58 (range, 22-77). Five patients presented with neurologic symptoms. The patients' medical records were retrospectively reviewed for imaging reports (cerebral angiography, computed tomography, or ultrasound) and available clinical follow-up. Brief telephone interviews with patients, immediate family, or care personnel were also used. Procedural and midterm complication rates were calculated.
Results:
Of 8 procedures, 7 (87.5%) resulted in no residual stenosis. The procedural stroke rate was 0 (0%) of 8 procedures. The procedural TIA rate was 2 (25%) of 8 procedures. The mean follow-up was 31.7 months (range, 11.3-75.9 months). In 2 cases, follow-up was clinical only. In the remaining cases, there were clinical and imaging follow-up in the form of cerebral angiography (n = 3), CT angiography (n = 2), and ultrasound (n = 1). There was one recurrent TIA at 30 days and again at 3.1 months (1/8, 12.5%). There were no strokes (0/8, 0%) and there were no TIAs in patients who were initially asymptomatic on presentation. There was one death from an unrelated cause.
Conclusion:
In this series, angioplasty and stenting were effective in relieving stenosis at the common carotid origin and have low rates of ischemic complications.
Related Concept Videos
Coronary Artery Disease V: Interprofessional Care
The Arch of Aorta
Encircling the heart, the coronary arteries form a ring-like structure before...
Angina IV: Management
Peripheral Artery Disease III: Interprofessional Care
Acute Coronary Syndrome I: Introduction
Aneurysm III: Interprofessional Care