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[Colonic poliposis and acromegaly. Colonoscopy prevalence and detection]
J Á Cancino-López1, J Garza-Sánchez, D E Dorantes-Díaz
1Servicio de Cirugía de Colon y Recto, UMAE Hospital de Especialidades Dr. Bernardo Sepúlveda G., Centro Médico Nacional Siglo XXI IMSS., Av. Cuauhtémoc 330, Col. Doctores, Del. Cuauhtémoc, C.P. 06720, Mexico, D.F.
Background:
The prevalence of colorectal polyps in the general population is 10%. Hormonal alterations in acromegaly stimulates adenomatose polyps development making that increase it prevalence. Colonoscopy has elevated sensibility and specificity in detection of colorectal adenomas.
Objective:
Identify colonic polyps in patients with acromegaly and establish the importance of colonoscopy as a detection method.
Material And Methods:
Retrospective, observational and descriptive study made in Colon and Rectum Surgery Department from March 2000 to March 2007 in patients with acromegaly and colonoscopy. Analyzed variables were: gender,age, endoscopy findings and histopathological results. Descriptive statistics were used to analysis of results.
Results:
Thirty-two patients were included: 14 (44%) men, 18 (56%) women. The mean age was 48 (range 22 to 75 years old). In 9 (28%) patients were detected colorectal polyps, predominately in the sigmoid. Fifteen polyps lesion were found: 7 (46.6%) adenomas: 5 (33.3%) tubular and 2 (13.3) villous, 6 (40%) hyperplasic, 1 (6.6%) inflammatory and 1 (6.6%) carcinoma. Colonoscopy was complete in 30 (93.7%) patients.
Conclusions:
The prevalence of colonic polyps inpatients with acromegaly undergoing colonoscopy,was 28%, higher than expected in the general population. Colonoscopy constitutes an important diagnosis technique in early neoplasia detection.
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