Related Experiment Video
Updated: Jun 21, 2026

Hyperglycemic Clamp and Hypoglycemic Clamp in Conscious Mice
Published on: January 26, 2024
The genesis and consequences of postprandial hyperglycemia
1Diabetes Care Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7172, USA. Jean_Dostou@med.unc.edu
Abstract:
Blood glucose levels after meals may be a misunderstood or overlooked aspect of management of type 2 diabetes. Emerging data suggest that postprandial glucose (PPG) excursions-meaning excessive increases in plasma glucose levels after meals-may be even more representative of overall glucose control than fasting glucose concentrations. In fact, evidence is accumulating that supports a close relationship between PPG levels and diabetes-related morbidity and mortality. Thus, interventions directed at postprandial glucose control could prove to be an effective and physiologic means of improving overall glucose homeostasis and reducing the incidence and progression of diabetic complications.
Related Concept Videos
Hyperglycemia
Type II Diabetes II: Pathophysiology
Hypoglycemia
Glucose Homeostasis: Regulation of Blood Glucose
During fasting, when blood glucose levels are low, the pancreas secretes glucagon. it...
Hypoglycemia and Glucagon
Hormones Regulating Blood Glucose
In addition to accelerating glucose uptake and utilization, insulin has...
