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Updated: Jun 21, 2026

Investigating Scarless Tissue Regeneration in Embryonic Wounded Chick Corneas
Published on: May 2, 2022
Histology of corneal wound healing after deep lamellar endothelial keratoplasty
Chaoran Zhang1, Jianjiang Xu, Rongjia Chen
1Ophthalmology Department, Eye and Ear Nose Throat Hospital, Fudan University, Shanghai, China. zhangchaoran@hotmail.com
Abstract:
Deep lamellar endothelial keratoplasty (DLEK) has become an alternative procedure for bullous keratopathy. Herein, the histopathological characteristics of corneal wound healing after DLEK were reported. A 71-year-old man suffering from left psuedophakia bullous keratopathy received small incision DLEK. Twenty months later, another penetrating keratoplasty (PK) was performed because of the graft failure. The histopathology of the corneal button removed during PK demonstrated the regularity of stromal fiber alignment at the graft interface. Fibrotic repair was limited to the peripheral margins.

