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Related Concept Videos

Acute Pancreatitis I: Introduction01:25

Acute Pancreatitis I: Introduction

Acute pancreatitis is the sudden inflammation of the pancreas caused by the early activation of digestive enzymes, leading to the autodigestion of pancreatic tissue. This results in local inflammation and, in severe cases, systemic complications.EtiologyUnderstanding the underlying causes is crucial, as identifying the etiology guides treatment and anticipates complications. Acute pancreatitis can be triggered by various factors, typically grouped into the following clinical categories.Biliary...
Acute Pancreatitis I: Introduction01:27

Acute Pancreatitis I: Introduction

Pancreatitis is inflammation of the pancreas, an organ located behind the stomach. It can be either acute or chronic.
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
Acute Pancreatitis II: Clinical Manifestations and Management01:30

Acute Pancreatitis II: Clinical Manifestations and Management

Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...
Chronic Pancreatitis I: Introduction01:24

Chronic Pancreatitis I: Introduction

The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
Chronic Pancreatitis I: Introduction01:25

Chronic Pancreatitis I: Introduction

Chronic pancreatitis is a long-standing, relapsing inflammation of the pancreas, characterized by irreversible damage to the gland. It results in progressive destruction of the pancreatic parenchyma, fibrosis, and eventual loss of both exocrine and endocrine function. The disease may evolve gradually after multiple episodes of acute pancreatitis or develop independently.EtiologyChronic pancreatitis can arise from a variety of causes:Alcohol use is the leading cause, accounting for 70–80% of...
Acute Pancreatitis II: Pathophysiology01:21

Acute Pancreatitis II: Pathophysiology

The pathophysiology of acute pancreatitis centers on injury to pancreatic acinar cells, which initiates a cascade of harmful intracellular events.This injury leads to premature activation of trypsinogen to trypsin in the pancreas. Trypsin then activates other digestive enzymes, such as chymotrypsin, elastase, and phospholipase A2, which begin breaking down pancreatic tissue. The resulting autodigestion causes local inflammation, tissue swelling, hemorrhage, and fat necrosis.Injured acinar cells...

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Related Experiment Video

Updated: Jun 21, 2026

Postoperative Ileus Murine Model
04:26

Postoperative Ileus Murine Model

Published on: July 12, 2024

Acute pancreatitis and ileus post colonoscopy.

Hin Hin Ko1, Trevor Jamieson, Brian Bressler

  • 1Department of Medicine, University of British Columbia, Vancouver, Canada.

Canadian Journal of Gastroenterology = Journal Canadien De Gastroenterologie
|August 12, 2009
PubMed
Summary

This case study reports the first instance of acute pancreatitis and ileus following a colonoscopy procedure. The patient recovered after a repeat colonoscopy and tube placement, highlighting a rare complication of the diagnostic procedure.

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Retroperitoneal Laparoscopic Debridement and Drainage for Pancreatic Abscess
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Retroperitoneal Laparoscopic Debridement and Drainage for Pancreatic Abscess

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Last Updated: Jun 21, 2026

Postoperative Ileus Murine Model
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Postoperative Ileus Murine Model

Published on: July 12, 2024

Retroperitoneal Laparoscopic Debridement and Drainage for Pancreatic Abscess
03:42

Retroperitoneal Laparoscopic Debridement and Drainage for Pancreatic Abscess

Published on: March 15, 2024

Area of Science:

  • Gastroenterology
  • Endoscopy
  • Abdominal Imaging

Background:

  • Colonoscopy is a common endoscopic procedure for colorectal cancer screening and diagnosis.
  • Post-polypectomy bleeding and perforation are known complications.
  • Acute pancreatitis and ileus are rare complications of colonoscopy.

Observation:

  • A 60-year-old woman presented with iron deficiency anemia.
  • She underwent colonoscopy with two polypectomies in the descending colon.
  • The procedure was complicated by abdominal distension and tenderness.

Findings:

  • Bloodwork revealed elevated amylase levels.
  • Abdominal imaging confirmed pancreatitis, particularly of the pancreatic tail.
  • Computed tomography showed a dilated cecum and air-fluid levels, indicative of ileus.

Implications:

  • This case represents the first reported instance of colonoscopy-associated pancreatitis and ileus.
  • The pancreatitis was likely caused by trauma to the pancreatic tail during the procedure.
  • Awareness of these rare complications is crucial for patient management.