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Economic evaluation of antipsychotic drugs for schizophrenia treatment within the Brazilian Healthcare System
Leandro Mendonça Lindner1, Antonio Carlos Marasciulo, Mareni Rocha Farias
1Programa de Pós-Graduação em Farmácia, Universidade Federal de Santa Catarina (UFSC), 88040-970 Florianópolis, SC, Brasil.
Objective:
To assess the cost-utility of first and second-generation antipsychotics for treatment of schizophrenia.
Methods:
A five-year Markov model was constructed based on a survey of the records of patients seen in 2006 at a psychosocial care center in the municipality of Florianopolis, Southern Brazil. Costs were evaluated from the perspective of the Sistema Unico de Saúde (SUS - Unified Healthcare System). Utility was measured in quality-adjusted life years obtained in the literature.
Results:
The Markov model indicated risperidone and haloperidol utilization before olanzapine as the most cost-effective alternatives.
Conclusions:
Antipsychotic agents haloperidol and risperidone are more cost-effective than olanzapine. Strategies prioritizing the use of antipsychotics with better cost-effectiveness could optimize resource allocation without necessarily compromising the health of patients treated through the Sistema Unico de Saúde.
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