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Updated: Jun 21, 2026

Generation and On-Demand Initiation of Acute Ictal Activity in Rodent and Human Tissue
Published on: January 19, 2019
Epilepsy and nonlinear dynamics
1Department of Epileptology, and Helmholtz-Institute for Radiation and Nuclear Physics, and Interdisciplinary Center for Complex Systems, University of Bonn, Bonn, Germany. klaus.lehnertz@ukb.uni-bonn.de
Abstract:
This overview summarizes findings obtained from analyzing electroencephalographic (EEG) recordings from epilepsy patients with methods from the theory of nonlinear dynamical systems. The last two decades have shown that nonlinear time series analysis techniques allow an improved characterization of epileptic brain states and help to gain deeper insights into the spatial and temporal dynamics of the epileptic process. Nonlinear EEG analyses can help to improve the evaluation of patients prior to neurosurgery, and with an unequivocal identification of precursors of seizures, they can be of great value in the development of seizure warning and prevention techniques.
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