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Updated: Jun 21, 2026

Fixed Volume or Fixed Pressure: A Murine Model of Hemorrhagic Shock
16:31

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Published on: June 6, 2011

Volume replacement in trauma.

Marcelo Augusto Fontenelle Ribeiro1, Marina Gabrielle Epstein, Luciana Daniela Lossurdo de Araujo Alves

  • 1Department of Surgery, Universidade Cidade De Sao Paulo Medical School, Sao Paulo, Brazil. mribeiro@cwaynet.com.br

Ulusal Travma Ve Acil Cerrahi Dergisi = Turkish Journal of Trauma & Emergency Surgery : TJTES
|August 12, 2009
PubMed
Summary

No consensus exists on the best fluids for trauma resuscitation. Current evidence suggests no clear benefit of colloid solutions over crystalloid fluids for volume replacement in trauma patients.

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Area of Science:

  • Emergency Medicine
  • Critical Care
  • Trauma Management

Background:

  • Fluid resuscitation is critical in managing multiple trauma patients.
  • Optimal fluid selection remains a debated topic in trauma care.

Purpose of the Study:

  • To compare different fluid types for volume replacement in trauma.
  • To review indications, mechanisms, and side effects of resuscitation fluids.

Main Methods:

  • Extensive literature review of indexed journals from 1997-2008.
  • Systematic review of available evidence on fluid resuscitation in trauma.

Main Results:

  • No consensus on ideal fluid for trauma resuscitation.
  • Systematic reviews show no benefit of colloids over crystalloids.
  • Hypertonic solutions expand blood volume and raise blood pressure.
  • Gelatins are largely discontinued due to limited efficacy and risks.

Conclusions:

  • Crystalloids are commonly used in trauma resuscitation.
  • No convincing evidence supports colloid superiority over crystalloids for volume restoration.