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Published on: January 3, 2018
New carvotanacetone derivatives from Sphaeranthus africanus
Consolacion Y Ragasa1, Po-Wei Tsai, Cecilia T Galvez
1Chemistry Department, De La Salle University and Center for Natural Sciences and Ecological Research, De La Salle University, Manila, Phillipines. ragasac@dlsu.edu.ph
Abstract:
The dichloromethane extract of the air-dried leaves of Sphaeranthus africanus afforded four new carvotanacetone derivatives (1, 2, 3A, and 3B). Their structures were elucidated by extensive 1D and 2D NMR spectroscopy. Compounds 1- 3 exhibited antibacterial activity against Staphylococcus aureus and Pseudomonas aeruginosa and antifungal activity against Candida albicans, Trichophyton mentagrophytes and Aspergillus niger.
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