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05:51
Measuring the Carotid to Femoral Pulse Wave Velocity (Cf-PWV) to Evaluate Arterial Stiffness
Published on: May 3, 2018
Vascular access localization determines regional changes in arterial stiffness.
Edmundo I Cabrera Fischer1, Daniel Bia, Rodolfo Valtuille
1Favaloro University, Buenos Aires, Argentina and National Council of Technical and Scientific Research (CONICET) - 1078 Buenos Aires, Argentina. fischer@favaloro.edu.ar
The Journal of Vascular Access
|August 12, 2009
Summary
Arteriovenous fistulae (AVF) construction in hemodialysis patients may reduce arterial stiffness in the access arm. This study found lower pulse wave velocity (PWV) in AVF arms compared to non-fistula arms, suggesting a potential impact on vascular health.
Area of Science:
- Cardiovascular research
- Nephrology
- Vascular surgery
Background:
- Vascular access (VA) dysfunction is a major cause of hospitalization for chronically hemodialyzed patients (CHP).
- Increased arterial stiffness is observed in patients with end-stage renal failure.
- Studies aim to reduce morbidity associated with VA construction.
Purpose of the Study:
- To evaluate arterial stiffness using pulse wave velocity (PWV) in the carotid-brachial pathway with arteriovenous fistulae (AVF).
- To compare arterial stiffness between pathways with and without VA in CHP.
Main Methods:
- PWV measurements were taken in 38 CHP.
- PWV was assessed in the carotid-femoral and bilateral carotid-brachial pathways.
- Clinical and biochemical parameters were also recorded.
Main Results:
- Carotid-brachial PWV was significantly lower in arms with AVF (10.07 m/s) compared to contralateral arms without VA (11.55 m/s).
- In diabetic CHP, AVF arms showed lower PWV (8.00 m/s) than non-diabetic hemodialyzed patients (NDHP) (10.38 m/s).
- Carotid-femoral PWV was higher in diabetic patients (16.87 m/s) than NDHP (14.06 m/s).
Conclusions:
- Carotid-brachial PWV is significantly lower in upper limbs with AVF compared to intact arteries in the contralateral pathway of CHP.
- This finding suggests a potential modification of arterial properties post-AVF creation.
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