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Updated: Jun 21, 2026

Implementation of Non-invasive Point of Care Transient Elastography for Evaluation of Liver Disease in Pediatric Populations with Cystic Fibrosis
Published on: August 29, 2025
Endocrine parameters of cystic fibrosis: back to basics
Michael S Stalvey1, Terence R Flotte
1Department of Pediatrics and the Gene Therapy Center, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA. michael.stalvey@umassmed.edu
Abstract:
Dramatic changes in the life expectancy of cystic fibrosis (CF) patients are occurring, creating a cohort of aging individuals experiencing long-term complications of this chronic disease. The two most common of these complications include CF-related diabetes and CF bone disease. The clinical implications of each have become better understood, as have potential therapies. However, data obtained from the basic science studies of both diseases have not been widely recognized. In this review, we focus on the known and hypothesized pathogenesis of these two disorders. Additionally, the molecular underpinnings of CF will be explained along with the potential interactions with endocrine disease phenotypes.
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