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Related Concept Videos

Mass Analyzers: Common Types01:19

Mass Analyzers: Common Types

The quadrupole mass analyzer consists of four cylindrical metal rods arranged in a diamond carrying a DC voltage and a radio-frequency AC voltage. The motion of ions through the quadrupole depends on the field strength, causing only ions of a certain m/z to resonate successfully and strike the detector at a given field strength. Though the transmission rate for these analyzers is high, the exact elemental composition of the sample is not determined because of low resolution; however, they are...
Electrospray Ionization (ESI) Mass Spectrometry01:12

Electrospray Ionization (ESI) Mass Spectrometry

Higher molecular weight biomolecules are nonvolatile compounds that may decompose before ionizing or vaporizing during mass analysis with conventional electron impact ionization methods. Accordingly, electrospray ionization (ESI) is the favored method for vaporizing and ionizing biomolecules as it circumvents rapid fragmentation and enables the recording of mass signals for the entire biomolecule.
ESI utilizes electrical energy to transfer ions from the liquid phase of the sample into the...
Inductively Coupled Plasma–Mass Spectrometry (ICP–MS): Overview01:19

Inductively Coupled Plasma–Mass Spectrometry (ICP–MS): Overview

In inductively coupled plasma–mass spectrometry (ICP–MS), an inductively coupled plasma (ICP) torch is used as an atomizer and ionizer. Solid samples are dissolved and volatilized before being introduced into the high-temperature argon plasma, while solution samples are nebulized and passed through the high-temperature argon plasma. Plasma dissociates the analytes and ionizes their component atoms to form a mixture of positive ions and molecular species. The positive ions are then passed on to...
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Mass Spectrometers

This lesson details the instrumentation of a mass spectrometer—a physical instrument to perform mass spectrometry on analyte molecules and record the characteristic mass spectra. This is achieved via three chief functions:
Inductively Coupled Plasma Atomic Emission Spectroscopy: Instrumentation01:26

Inductively Coupled Plasma Atomic Emission Spectroscopy: Instrumentation

Inductively coupled plasma (ICP) is the common plasma source used in atomic emission spectroscopy (AES), a technique that detects and analyzes various elements in a sample. This method is often called inductively coupled plasma atomic emission spectroscopy (ICP-AES).
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Mass Analyzers: Overview01:13

Mass Analyzers: Overview

The mass analyzer is a crucial component of the mass spectrometer. In the ionization chamber, the vaporized sample is bombarded with a high-energy electron beam to generate a radical cation and further fragment into neutral molecules, radicals, and cations. A series of negatively charged accelerator plates accelerate the cations into the mass analyzer. The mass analyzer separates ions according to their mass-to-charge (m/z) ratios and then directs them to the detector. The common types of mass...

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Preparing an Isotopically Pure 229Th Ion Beam for Studies of 229mTh
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Published on: May 3, 2019

Mass-selective axial ejection from a linear ion trap with a direct current extraction field.

Masuyuki Sugiyama1, Hideki Hasegawa, Yuichiro Hashimoto

  • 1Central Research Laboratory, Hitachi, Ltd., Tokyo, Japan. masuyuki.sugiyama.bp@hitachi.com

Rapid Communications in Mass Spectrometry : RCM
|August 12, 2009
PubMed
Summary

A novel mass-selective axial ejection method for linear ion traps (LIT) was developed. This technique achieves a mass resolving power of 1300 and an ejection efficiency of 20% at 500 Th/s, enhancing ion analysis capabilities.

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Area of Science:

  • Analytical Chemistry
  • Mass Spectrometry
  • Ion Optics

Background:

  • Linear ion traps (LIT) are crucial for mass spectrometry.
  • Efficient mass-selective ion ejection is essential for high-performance analysis.
  • Existing methods face limitations in speed and efficiency.

Purpose of the Study:

  • To introduce a new mass-selective axial ejection method for linear ion traps.
  • To enhance ion manipulation and extraction within a linear ion trap.
  • To improve the speed and resolution of mass spectrometry analysis.

Main Methods:

  • Development of a mass-selective axial ejection technique using orthogonal trap and extraction wire lenses.
  • Utilizing resonant excitation with supplemental AC voltage applied to excitation lenses.
  • Employing a direct current (DC) extraction field for ion ejection.
  • Investigation through both simulation and experimental analysis.

Main Results:

  • Achieved a mass resolving power of m/Δm = 1300 at a scan rate of 500 Th/s.
  • Demonstrated an ejection efficiency of 20% at a scan rate of 500 Th/s.
  • Optimized ejection efficiency through adjustment of trap wire lens DC bias.

Conclusions:

  • The developed method enables efficient and selective ion ejection from a linear ion trap.
  • This technique offers a significant advancement in mass spectrometry instrumentation.
  • The optimized parameters provide high performance for rapid ion analysis.