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Published on: December 3, 2021
Mortality after first myocardial infarction in Greek patients: a 4-year follow-up study
Genovefa D Kolovou1, Constantinos Mihas, Anastasia Kotanidou
1First Cardiology Department, Onassis Cardiac Surgery Center, Athens, Greece. genovefa@kolovou.com
Insights
Smoking cessation and increased physical activity are crucial for coronary heart disease (CHD) survivors after myocardial infarction (MI). Early intervention in antismoking programs can improve outcomes.
Area of Science:
- Cardiology
- Public Health
- Epidemiology
Background:
- Coronary heart disease (CHD) mortality is influenced by time since myocardial infarction (MI) and risk factor management.
- Understanding post-MI survival factors is critical for patient outcomes.
Purpose of the Study:
- To investigate mortality risk factors in patients following myocardial infarction (MI).
- To identify lifestyle and medical factors associated with long-term survival after MI.
Main Methods:
- Observational, retrospective 4-year follow-up study.
- 804 patients (628 men) completed questionnaires on lifestyle, medical history, and medications.
- Data analyzed for associations with mortality.
Main Results:
- 12% of men and 15% of women died during follow-up.
- Older age, longer smoking duration, and exercise frequency differed significantly between survivors and deceased.
- Multivariate analysis linked increased smoking years and nitrate treatment to higher mortality, while increased exercise frequency was associated with lower mortality.
Conclusions:
- Emphasize smoking cessation and increased physical activity for MI survivors.
- Implement antismoking programs starting at an early age to improve long-term prognosis.
Background:
Death associated with coronary heart disease (CHD) depends in part on the time since the myocardial infarction (MI) and modification of risk factors.
Methods:
This observational, retrospective 4-year follow-up study consisted of 804 patients (628 men). The participants completed a questionnaire reporting diet, demographic factors, personal behavior (smoking, physical activity), anthropometry, prior medical conditions (hypertension, diabetes mellitus), and recent medication.
Results:
During 48 months of follow-up, 12% of men and 15% of women died. Older age, longer duration of smoking, and frequency of exercise were significantly different between survivors and the deceased (P = .014, P = .014, P = .001, respectively). Multivariate analysis revealed associations with years of smoking (odds ratio, OR: 1.10, P = .025), treatment with nitrates (OR: 4.81, P = .024), and increased frequency of exercise (OR: 0.42, P = .013), adjusting for age and gender.
Conclusions:
We should emphasize cessation of smoking and increased physical activity in MI survivors. Antismoking programs should start at an early age.
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