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Updated: Jun 21, 2026

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Prolonged survival in a patient with choroidal metastases from urothelial bladder cancer
Kirsty L Wiltshire1, Norman Laperriere, Robert G Bristow
1Department of Radiation Oncology, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia and the.
Abstract:
Choroidal metastases secondary to urothelial carcinoma are extremely rare and are usually associated with an extremely poor prognosis. We present a case of an 88-year-old man with newly diagnosed urothelial carcinoma of the bladder who presented with acute loss of vision before commencing definitive concurrent chemoradiotherapy to the bladder. Ophthalmological examination demonstrated bilateral choroidal metastases. He received palliative radiotherapy to the orbits and completed his planned radiotherapy to the bladder. He remained disease-free at last follow-up 4 years after the completion of treatment. We review the literature particularly with regard to diagnosis and management of choroidal metastases. Choroidal metastases should be considered in a patient with a history of urothelial cancer presenting with new onset of eye symptoms.
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