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Related Concept Videos

Tonsillitis I: Introduction01:30

Tonsillitis I: Introduction

Tonsillitis is inflammation of the tonsils, which are two lymphoid tissue masses at the back of the throat. This condition can cause discomfort and irritation in the throat.
Etiology
Three primary contributing factors have been identified.
Acute Pharyngitis01:30

Acute Pharyngitis

Introduction
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
Chronic Pharyngitis01:23

Chronic Pharyngitis

Chronic pharyngitis refers to persistent inflammation of the pharyngial mucosa.
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
Microbiome of the Eye01:22

Microbiome of the Eye

The human eye has a specialized microbiota that reflects its unique anatomical and immunological environment. This low-biomass microbial community predominantly colonizes the conjunctiva and eyelid margins, playing a vital role in ocular surface homeostasis and defense. Despite its proximity to the richly colonized facial skin, the ocular surface maintains a distinct microbial profile due to continuous mechanical and biochemical defense mechanisms.The conjunctival surface hosts fewer microbial...
Streptococcal Pharyngitis01:27

Streptococcal Pharyngitis

Streptococcal pharyngitis, commonly known as “strep throat,” is an acute infection of the oropharyngeal tissues caused by the Gram‑positive Group A Streptococcus (Streptococcus pyogenes). Transmission occurs primarily through respiratory droplets expelled during coughing, sneezing, or talking.Mechanisms of Host Entry and Immune EvasionUpon entering the host, S. pyogenes adheres to the mucosal epithelial cells of the pharynx via surface proteins, notably lipoteichoic acid and the antiphagocytic...
Tonsillitis II: Management01:26

Tonsillitis II: Management

This lesson will focus on the different treatment options for managing tonsillitis, which typically depend on the cause and severity.

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Related Experiment Video

Updated: Jun 21, 2026

Nasolacrimal Lavage as a Treatment for Ocular Surface Toxic Soup Syndrome
03:40

Nasolacrimal Lavage as a Treatment for Ocular Surface Toxic Soup Syndrome

Published on: April 25, 2025

[Stomatitis, cheilitis and conjunctivitis after a common cold].

M Jakob1, N Stuhrmann, J Jordan

  • 1Klinik für Hals-Nasen-Ohren-Heilkunde/Chirurgie, Rheinische Friedrich-Wilhelms-Universität, Sigmund-Freud-Strasse 25, 53105, Bonn, Deutschland. mark.jakob@ukb.uni-bonn.de

HNO
|August 13, 2009
PubMed
Summary

Fuchs' syndrome is a severe drug-induced skin reaction causing painful mouth sores and fever. Promptly stopping the causative medication and initiating cortisone therapy are crucial for recovery.

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Area of Science:

  • Dermatology
  • Pharmacology
  • Internal Medicine

Background:

  • Fuchs' syndrome, a severe mucocutaneous drug reaction, presents with significant patient morbidity.
  • Early diagnosis and intervention are critical for managing this condition.

Observation:

  • A 24-year-old female presented with odynophagy, rhinitis, apathy, and fever, unresponsive to initial analgesics.
  • Physical examination revealed extensive erosive, edematous, and fibrin-covered mucosal lesions of the oral, pharyngeal, and laryngeal areas, along with conjunctivitis and cheilitis.

Findings:

  • Laboratory findings included leukocytosis and elevated C-reactive protein.
  • The clinical presentation and patient history led to the diagnosis of Fuchs' syndrome, a severe medication-induced skin reaction.

Implications:

  • Discontinuation of the offending medication is paramount for patient recovery.
  • Early initiation of corticosteroid therapy significantly impacts treatment outcomes in Fuchs' syndrome.