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Updated: Jun 21, 2026

Chronic Salmonella Infection Induced Intestinal Fibrosis
Published on: September 22, 2019
Clinical aspects of inflammatory bowel disease
Britta Siegmund1, Martin Zeitz
1Charité Universitätsmedizin Berlin, Campus Benjamin Franklin, Medizinische Klinik I, Gastroenterology/Rheumatology/Infectious Diseases, Germany.
Abstract:
Inflammatory bowel disease (IBD) accompanies its patients throughout life. Current treatment options do not lead to a cure and are accompanied by significant toxicities. Numerous animal models contributed to the understanding of the pathogenesis of the disease and led to the development of novel treatment strategies. Genome-wide association analysis added a novel dimension. Here, we discuss how characterization of mutated genes in animal models supports the identification of future therapeutic targets.
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