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Updated: Jun 21, 2026

Endoscopic Injection Sclerotherapy Assisted by Cyanoacrylate and Clips for Gastroesophageal Varices
Published on: June 13, 2025
Sepsis caused by endoscopic clipping for colonic diverticular bleeding: a rare complication
Keiichiro Kume1, Masahiro Yamasaki, Ichiro Yoshikawa
1Third Department of Internal Medicine, University of Occupational and Environmental Health, Japan, School of Medicine, 1-1, Iseigaoka, Yahatanishi-ku, Kitakyusyu 807-8555, Japan. k-kume@med.uoeh-u.ac.jp
Abstract:
We herein report the rare complication of sepsis caused by endoscopic clipping for colonic diverticular bleeding. A 78-year-old man with a 12-h history of near syncope and painless hematochezia was admitted to our hospital. Following the transfusion of 4 U of blood and continued hematochezia, a colonoscopy was performed. Active bleeding was seen as continuous arterial spurting from a single diverticulum located in the middle ascending colon. This diverticulum was seamed by four endoclips. The next day, the patient became febrile with a temperature of 39.2 degrees C. Laboratory data included a white blood cell count of 18 100/mm(3) and a C-reactive protein level of 3.4 mg/dL. He was diagnosed with sepsis since Escherichia coli was detected in the blood culture. Antibiotics were started. Four days later his fever had improved and laboratory data improved 9 d later.
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