Related Experiment Video

Updated: Jun 21, 2026

Detection of Invasive Pulmonary Aspergillosis in Haematological Malignancy Patients by using Lateral-flow Technology
08:01

Detection of Invasive Pulmonary Aspergillosis in Haematological Malignancy Patients by using Lateral-flow Technology

Published on: March 22, 2012

Trends in invasive fungal infections, with emphasis on invasive aspergillosis

Z Erjavec1, H Kluin-Nelemans, P E Verweij

  • 1Department of Internal Medicine, Ommelander Groep-Delfzicht Hospital, Delfzijl, The Netherlands. z.erjavec@ozg.eu

Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases
|August 14, 2009
PubMed

Insights

Invasive fungal infections, particularly Aspergillus mould infections, are rising. New diagnostic tools and understanding host factors are crucial for early detection and effective treatment of these infections.

Area of Science:

  • Mycology
  • Infectious Diseases
  • Clinical Microbiology

Background:

  • Invasive fungal infections (IFIs) show evolving epidemiological patterns.
  • Yeast infections remain stable, but infections caused by Aspergillus species are increasing.
  • Accurate diagnosis of mould infections is challenging, necessitating advanced identification techniques.

Purpose of the Study:

  • To highlight the changing landscape of invasive fungal infections.
  • To emphasize the need for validated diagnostic techniques for mould infections.
  • To underscore the importance of early diagnosis and susceptibility testing for guiding antifungal therapy.

Main Methods:

  • Review of current diagnostic advancements in IFIs.
  • Discussion of emerging biological markers like PCR, galactomannan, and 1,3 beta-D-glucan.
  • Exploration of host factors and risks associated with new treatment modalities.

Main Results:

  • Increasing incidence of Aspergillus infections requires improved diagnostic accuracy.
  • Biological markers are undergoing clinical validation for earlier detection.
  • Early diagnosis significantly correlates with improved patient survival rates.

Conclusions:

  • Accurate diagnosis and in vitro susceptibility testing are imperative for managing IFIs.
  • Understanding host susceptibility and treatment risks is vital for invasive mould infections.
  • Continued research is essential to address evolving IFI epidemiology and antifungal resistance.

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