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Male Sexual Response: Erection & Ejaculation

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Related Experiment Video

Updated: Jun 21, 2026

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility

Published on: May 30, 2025

Premature ejaculation.

Chris G McMahon¹

¹Australian Centre For Sexual Health Suite 2-4, Berry Road Medical Centre 1a Berry Rd St. Leonards, Australia.

Indian Journal of Urology : IJU : Journal of the Urological Society of India

|August 14, 2009

Summary

Premature ejaculation (PE) is a common male sexual disorder. Selective serotonin re-uptake inhibitors (SSRIs) and dapoxetine offer effective treatment options, improving ejaculatory control and sexual satisfaction with minimal side effects.

Keywords:

PDE-5 inhibitors Premature ejaculation; selective serotonin reuptake inhibitors dapoxetine intravaginal ejaculatory latency time

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Treatment of Ejaculatory Duct Obstruction by Seminal Vesiculoscopy Assisted Flow Modification

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Published on: December 8, 2023

Area of Science:

Sexual Medicine
Pharmacology
Urology

Background:

Premature ejaculation (PE) is a prevalent male sexual disorder.
Definite PE is characterized by an intravaginal ejaculatory latency time (IELT) under 1 minute.
Potential contributing factors include sexual anxiety and altered central serotonin receptor sensitivity.

Purpose of the Study:

To review the current understanding and treatment of premature ejaculation (PE).
To highlight the efficacy of pharmacological interventions in managing PE.
To discuss the role of selective serotonin re-uptake inhibitors (SSRIs) and investigational drugs like dapoxetine.

Main Methods:

Review of existing literature on PE etiology and treatment.
Analysis of pharmacological approaches, including off-label SSRIs and specific agents like dapoxetine.
Evaluation of treatment outcomes, focusing on IELT, ejaculatory control, and sexual satisfaction.

Main Results:

Pharmacological modulation of the ejaculatory threshold is well-tolerated.
SSRIs can lead to improved ejaculatory control and sexual function within days.
Dapoxetine offers on-demand dosing with significant improvements in IELT and satisfaction, alongside minimal adverse effects.

Conclusions:

Pharmacological treatments, including SSRIs and dapoxetine, are effective for managing PE.
These treatments offer improved ejaculatory control, sexual satisfaction, and convenience.
Further research into the etiology and optimal treatment of PE is warranted.