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Updated: Jun 21, 2026

Preoxygenation Techniques for Tracheal Intubation in Critically Ill Adults Utilizing Oxygen Mask and Noninvasive Ventilation
Published on: December 5, 2025
Central venous oxygen saturation and emergency intubation--another piece in the puzzle?
Wolfgang Stahl1, Peter Radermacher, Michael Georgieff
1Universitätsklinik für Anästhesiologie, Universität Ulm, Steinhövelstrass, 89073 Ulm, Germany. wolfgang.stahl@uni-ulm.de
Abstract:
A recent multicentre observational study examined the effect of emergency intubation on central venous oxygen saturation (SCVo2) in critically ill patients. The main finding was that SCVo2 significantly increases 15 minutes after emergency intubation and institution of mechanical ventilation with 100% oxygen, especially in those patients with pre-intubation SCVo2 values <70%, regardless of whether these patients suffered from severe sepsis. However, in only one-quarter of this subgroup was the SCVo2 normalized to > or =70% solely by this intervention. In contrast, in patients with pre-intubation SCVo2 > or =70%, the SCVo2 failed to increase after intubation. A rise in SCVo2 can be expected when whole body oxygen extraction remains unchanged after intubation and ventilation with pure oxygen.
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